Quaternary Structure

Complexes of 2 or more polypeptide chains held together by noncovalent forces but in precise ratios and with a precise 3-D configuration.

The noncovalent association of a molecule of beta-2 microglobulin with the heavy chain of each class I histocompatibility molecule is an example. Compare:
Primary Structure
Secondary Structure
Tertiary Structure

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19 June 1999